The Great Lakes Conference has (mostly) settled its schedule for this fall.
While the specific dates aren't confirmed (games might be on the Friday, Saturday, and Sunday, but haven't been confirmed as to the specific day). Week 1 is the weekend of September 11, and then Week 2 is the weekend of September 18, and so on.
Bethel College is no longer in the Great Lakes Conference and its future in rugby is in serious doubt. Joining the conference is Adrian College, where Head Coach Benny Mateialona has been very successful in recruiting and building the nascent program.
In GRR's last DII rankings of the fall of 2019, two current Great Lakes teams were ranked—Grand Valley State at #23 and Central Michigan at #27.
Fall 2021 Great Lakes Conference Schedule
| Week 1 | Oakland | at | Grand Valley State | Great Lakes |
| Week 2 | Calvin College | at | Oakland | Great Lakes |
| Week 2 | Central Michigan | at | Grand Valley State | Great Lakes |
| Week 2 | Eastern Michigan | at | Saginaw Valley State | Great Lakes |
| Week 3 | Ferris State | at | Oakland | Great Lakes |
| Week 3 | Saginaw Valley State | at | Calvin College | Great Lakes |
| Week 3 | Central Michigan | at | Adrian College | Great Lakes |
| Week 3 | Eastern Michigan | at | Grand Valley State | Great Lakes |
| Week 4 | Ferris State | at | Central Michigan | Great Lakes |
| Week 4 | Adrian College | at | Grand Valley State | Great Lakes |
| Week 4 | Oakland | at | Saginaw Valley State | Great Lakes |
| Week 4 | Calvin College | at | Eastern Michigan | Great Lakes |
| Week 5 | Saginaw Valley State | at | Central Michigan | Great Lakes |
| Week 5 | Grand Valley State | at | Calvin College | Great Lakes |
| Week 5 | Adrian College | at | Oakland | Great Lakes |
| Week 5 | Ferris State | at | Eastern Michigan | Great Lakes |
| Week 6 | Oakland | at | Central Michigan | Great Lakes |
| Week 6 | Grand Valley State | at | Saginaw Valley State | Great Lakes |
| Week 6 | Adrian College | at | Ferris State | Great Lakes |
| Week 7 | Central Michigan | at | Calvin College | Great Lakes |
| Week 7 | Saginaw Valley State | at | Adrian College | Great Lakes |
| Week 7 | Grand Valley State | at | Ferris State | Great Lakes |
| Week 7 | Oakland | at | Eastern Michigan | Great Lakes |
| Week 8 | Calvin College | at | Adrian College | Great Lakes |
| Week 8 | Saginaw Valley State | at | Ferris State | Great Lakes |
| Week 8 | Eastern Michigan | at | Central Michigan | Great Lakes |
| Week 9 | Great Lakes Playoffs | Great Lakes |
